MIDI in a browser without the need for a plugin. Definitely worth a closer look at some point.
MIDI.js (on github) ties together, and builds upon frameworks that bring MIDI generation to the browser. Combine it with jasmid to create a web-radio MIDI stream similar to this demo… or with Three.js, Sparks.js, or GLSL to create Audio/visual experiments. Piano/guitar simulations, Drum machines, MIDI recording, and all kinds of certified funkitude is within your grasps!